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  Novartis Oncology na MA 7/31/2010
Developmental and Molecular Pathways Assay Development Scientist
The candidate should have a B.S. or M.S. degree or equivalent in biochemistry, cell biology, engineering or similar with 3+ years of industrial or academic research. Must be highly collaborative, self-motivated, results focused, team-oriented, and have excellent communication and computer skills.
  Novartis Oncology na MA 7/31/2010
Bioinformatics, Business Analyst (Metabolism and Pharmacokinetics)
Qualifications: ? Idea candidate should have an advanced degree in biology and/or B.S in Computer Science ? At least 3-5 years experience in a scientific or biotech environment and familiar with the ADME/PK/PD process flow in the context of drug discovery ? Strong communications and interpersonal skills ? Proven capabilities interacting with scientists and being customer service oriented ? Ability to work independently and/or as part of a team ? Extensive knowledge in the biology, especially about the drug metabolism and pharmacokinetics research process, ? Good understanding and practical experience in data management and data analysis tools to support research process ? Solid understanding of relational databases and familiarity with Oracle and/or SQL server ? Knowledge of web-based software development will be a strong plus
  Novartis Oncology na MA 7/31/2010
Senior PhD Scientist: Protein Purification and Expression
The Lab Leader of protein expression and purification group will possess the following qualifications: ?PhD with a minimum of five years of research in protein expression, purification, biochemistry or closely related discipline. ?General knowledge of state-of-the art technologies, platforms and approaches which enable practical yet innovative ways to support drug discovery programs. ?Thorough understanding of protein chemistry, biochemistry, bacterial, yeast and mammalian expression systems for tool generation to ensure the success of target-driven drug discovery. ?Strong command of academic or commercial research efforts and of scientific literature, and knowledge of key opinion leaders in the area. The Leader of protein group will be a decisive and results-oriented individual who is flexible, team-oriented, creative and able to excel in a multi-project, fast-track environment. He or she will be a strategic thinker who interacts and collaborates with project teams, peers and management in identifying and achieving discovery goals from both scientific and strategic perspectives.
  Novartis Oncology na MA 7/31/2010
Protein Production Scientist (BS/MS)
B.S/M.S or equivalent in biochemistry or a related discipline with at least 3 years of research laboratory experience. A strong background in protein expression and purification is highly desirable. The successful candidate will be expected to be able to participate in experimental design and to independently conduct experiments. They much also be detail oriented and be able to handle multiple tasks efficiently. The candidate must possess good communication skills and be comfortable working in a matrix based team environment.
  Novartis Oncology na MA 7/31/2010
Bioinformatics, Business Analyst (Translational Sciences/ETL Tools)
?Bachelor's degree in computer science and/or advanced degree in biology ?At least 3-5 years experience in application development in a drug discovery, scientific or biotech environment ?Basic understanding of regulatory requirements/compliance policies (e.g. GLP) ?Strong communications and interpersonal skills ?Solid understanding of ETL tools ?Proven capabilities interacting with scientists and being customer service oriented ?Ability to work independently and/or as part of a team ?Knowledge in biology, biological research processes, and applications ?Good understanding and practical experience in fundamentals of software engineering ?Solid understanding of relational databases and familiarity with Oracle and/or SQL server
  Novartis Oncology na MA 7/31/2010
Senior Scientist Molecular Diagnostics
Education: PhD in Biochemistry, Molecular Biology or a related discipline with 5+ years post-graduate research and development experience in infectious disease, genetic disorder or cancer. Languages: English Qualifications: In-depth knowledge of nuclear acid biochemistry and 2+ years of molecular assay and sample processing development experiences in IVD industry Strong background in high-sensitivity nucleic acid amplification and detection coupled with automated sample processing platforms and technologies, extensive experience in the development of DNA/RNA based assays to detect genetic variation and mutation. Hands-on experience on nucleic acid sample preparation, PCR, RT-PCR, gel electrophoresis, cloning, gene expression, microarray, DNA sequencing, allele specific PCR, Real time PCR, melting curve analysis, SNP/single point mutation detection, cell culture. Proven scientific achievements and track record for innovation; hands on experiences with statistics tools, Minitab or JMP, and bioinformatics tools. Knowledge of DFSS, understanding the principles of DOE and working experience and knowledge of cGMP practices, documentations and quality control system are highly desirable. A great team player in multidisciplinary environment, capable of multiple tasking and able to be fully committed to product development timelines. Excellent verbal and writing skills and strong communication skills are essential.
  Novartis Oncology na MA 7/31/2010
PhD Scientist: Antibody Therapeutics
Molecular Biology lab head Qualifications: ? Ph.D. in molecular biology or life science ? Minimum 3 years of post-doctoral experience in life-science and/or antibody therapeutic research. Industry experience is a plus. ? Self-driven and creative personality ? Excellent written and oral communication skills ? Extensive experience in molecular biology, cell and biochemical assay development and analysis
  Novartis Oncology na MA 7/31/2010
Small Molecule NMR Scientist (B.S./ M.S.)
M.S. or equivalent with 0-5 years or more relevant experience in small molecular NMR with demonstrated success in modern NMR methodologies. Demonstrated skills in data collection and process, spectral interpretation, data management and instrument maintenance are essential. A background in organic chemistry and a keen interest to champion NMR based collaborative research projects with medicinal chemists are required. Proficiency in UNIX/LINUX and expertise in hyphenated NMR technologies are desirable. Excellent communication skills and the ability to multitask in a fast-paced environment are essential. A self-motivated individual as well as a strong team player is required.
  Novartis Oncology na MA 7/31/2010
Molecular and Cellular Biology Research Scientist (BS/MS)
? B.S/M.S. in Biochemistry, Cell Biology or Molecular Biology ? Minimum 5 years experience in biochemistry, mammalian cell biology working with various cell lines and/or cell signaling mechanisms ? Previous experience with stable cell line production, design and analysis of cell-based assays, transfection and viral transduction technologies and RNAi techniques is required. ? Proficiency in the use of molecular biology and protein biochemistry technologies, e.g. DNA cloning, Real-time PCR, protein-protein interaction, and enzymatic assays is preferred. ? Familiar with different technologies to monitor cellular events (proliferation assays, high content imaging, technologies to monitor the state of signaling molecules in cellular extracts). ? Must be highly motivated, team-oriented, and have excellent interpersonal and communication skills.
  Novartis Oncology na MA 7/31/2010
Pathways Cellular/Molecular Scientist (BS/MS)
Minimum requirements MS in Biochemistry, Molecular Biology, Cell Biology, with 5-10 years of laboratory research experience. ? Thoroughly familiar with culturing various mammalian cell lines and primary cells, generating stable cell lines, designing cell-based and biochemical assays, and executing small molecule screens. ? Outstanding molecular biology techniques including DNA cloning, DNA/RNA preparation and characterization (SB, NB, qPCR). ? Exceptional expertise in genetic screening with siRNA/shRNA/cDNA by conventional and viral transduction technologies. ? Proficient in various techniques of protein expression, purification and functional characterization (WB, Co-IP, ELISA, luciferase assay). ? Experience with fluorescent imaging, flow cytometry. ? Excellent communication skills and usage of data analysis software.
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