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| Novartis Oncology |
na |
MA |
11/20/2009
|
| Pathways Research Scientist (BS/MS) |
| ?BS or MS in Biochemistry, Molecular Biology, or Cell Biology, with 5+ years of laboratory research experience.
? Extensive experience with culturing various mammalian cell lines, utilizing both 2D and 3D culture systems, designing cell-based assays, generating stable cell lines, and executing small molecule screens with laboratory automation equipment.
? Experience with high content imaging and designing/executing high content imaging-based screens.
? Outstanding molecular biology techniques including complex DNA cloning, site-directed mutagenesis, and qPCR.
? Exceptional expertise in genetic screening with siRNA/shRNA/cDNA by conventional and viral transduction technologies.
? Proficient in various protein analysis techniques, including, but not limited to, ELISA assays, immunoprecipitations, and western blots.
?Excellent communication skills |
| Novartis Oncology |
na |
MA |
11/20/2009
|
| Histotechnology Research Scientist (BS/MS) |
| The ideal candidate will have a BS or MS degree in a biological or chemical science discipline plus at least 4 years of histology experience. Strong organizational skills, self-motivation, attention to detail, flexibility, proactive willingness and desire to engage in the laboratory workflow, and an ability to contribute to a team environment are essential. Candidates should have experience working in a fast-paced, high volume, high productivity and quality environment, in either an industry or clinical laboratory. Experience and proficiency with immunohistochemistry methodology and image analysis is strongly preferred. Prior experience in cell biology and/or molecular biology techniques is preferred. |
| Novartis Oncology |
na |
MA |
11/20/2009
|
| Group Head, Biochemical & Organ Toxicology (Cambridge) |
| We are seeking an experienced scientist and manager to lead a Biochemical & Organ Toxicology group within Investigative Toxicology (Preclinical Safety, Translational Sciences) based in Cambridge, MA. Investigative Toxicology is using non-clinical innovative investigations to discover the mechanisms of target organ toxicity and to prevent and solve pre-clinical and clinical drug safety issues. The candidate will be responsible for the design and set-up of new experimental facilities for 3 laboratories, and the management of staff therein. The candidate will also be responsible for subsequent development, implementation and management of experimental studies. The primary deliverable of these laboratories (Endocrine & Repro-toxicology, Protein & Mitochondrial Toxicology and Biochemical & Cellular Toxicology) will be to facilitate the early identification and characterisation of toxicities during preclinical phases of drug development with a particular focus on Novartis Institute for Biomedical Research (NIBR) disease areas, expertise and technologies in Cambridge. In addition, the candidate will also work closely with Preclinical Safety Project Team Representatives to help assess potential safety liabilities associated with novel drugs and their target(s). The candidate will report to the Global Head of Biochemical and Organ Toxicology and will interact closely with colleagues in other groups as a member of cross-functional and multi-disciplinary teams (including global Investigative Toxicology & Preclinical Safety departments, NIBR and external collaborators). |
| Novartis Oncology |
na |
MA |
11/20/2009
|
| Pharmacokinetics Research Scientist (BS/MS) |
| Candidates will need a M.Sc or B.Sc, or
equivalent in Pharmaceutical Sciences,
Pharmacology or related field.
Candidates possessing 3 or more years of
industrial experience in pharmacokinetics
and drug metabolism. Experience with pre-
clinical pharmacokinetic protocol design and
experience working with Watson or LIMS is
desirable. Proven ability to design and
manage both routine and mechanistic animal
PK studies and to prudently manage and
implement studies to drive drug discovery
efforts. Experience with non-compartmental
techniques and pharmacokinetic modeling
software (e.g., WinNonlin or equivalent) is
highly desired. A successful candidate will
need excellent interpersonal skills,
particularly oral and written communication
skills and the ability to multitask. |
| Novartis Oncology |
na |
NJ |
11/20/2009
|
| Scientist, NPKPD |
| M.S. degree in biological or related sciences. Research experience using animal models is mandatory. Small animal surgical experience is highly desired. Good verbal and written communication skills are essential. The knowledge of radiochemistry, tissue distribution, metabolism and pharmacology is desirable. Prior work experience with PK/PD or statistical analysis and a demonstrated ability to work with modeling tools and databases (e.g. WinNonlin, GastroPlus, Watson, Spotfire, etc) is a plus. |
| Novartis Oncology |
na |
NJ |
11/20/2009
|
| Senior Scientist (Pharmacokinetics) |
| M.S. degree in biological or related sciences with minimal 3 years laboratory experience. Research experience using animal models is mandatory. Small animal surgical experience is highly desired. Excellent verbal and written communication skills are essential. The knowledge of radiochemistry, tissue distribution, metabolism and pharmacokinetics is desirable. Prior work experience with PK/PD analysis and a demonstrated ability to work with modeling tools and databases (e.g. WinNonlin, GastroPlus, Watson, Spotfire, etc) is a plus.
THIS REQUISITION APPROVED BY TSLT ON 1-JULY-2009 AND MOVED TO CRITICAL HIRE LIST. |
| Novartis Oncology |
na |
NJ |
11/20/2009
|
| Clinical Research Scientist/Sr. CRS |
| 1. Minimum 2 years experience in drug development for CRS role. Clinical trial experience preferred.
2. Basic working knowledge of clinical database systems
3. Knowledge of clinical trial design; basic statistics and pharmacokinetics a plus.
4. Solid medical/scientific writing skills; ability to effectively communicate across the business organization
5. Knowledge of Oncology therapeutic area
6. Knowledge of good clinical practices (GCP/ICH) and regulatory requirements.
7. Ability to collaborate and work effectively in teams.
8. Demonstrates competencies in line with established profile.
9. Ability to manage multiple projects simultaneously.
10. Effectively manage project goals/objectives and timelines.
11.Collaborate with cross functional areas to support project deliverables.
12.Up to 20% travel |
| Novartis Oncology |
na |
MA |
11/20/2009
|
| Ph.D Scientist: Oncology Biotherapeutics |
| Biotherapeutics lab head Qualifications:
? Ph.D. molecular biology or related field.
? Minimum 3 years of post-doctoral experience in cancer and/or antibody therapeutic research.
? Independent, self motivated and innovative personality
? Excellent written and oral communication skills
? Extensive experience in cell and biochemical assay development and analysis |
| Novartis Oncology |
na |
MA |
11/20/2009
|
| PhD Scientist: Antibody Therapeutics |
| Molecular Biology lab head Qualifications:
? Ph.D. in molecular biology or life science
? Minimum 3 years of post-doctoral experience in life-science and/or antibody therapeutic research. Industry experience is a plus.
? Self-driven and creative personality
? Excellent written and oral communication skills
? Extensive experience in molecular biology, cell and biochemical assay development and analysis |
| Novartis Oncology |
na |
MA |
11/20/2009
|
| Molecular/Cellular Biology Research Scientist (BS/MS) |
| B.S or M.S scientist with at least 3 years of relevant research experience; the candidate has strong background in cellular and molecular biology. Previous experience in the study of innate immunity is highly desirable; experience in cellular immunology and in vivo biology is advantageous. Experience with large dataset analysis is a plus. The candidate is expected to possess strong problem solving and analytical skills, and be capable of independent thinking. Excellent communication and organization skills are required. |
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