At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly. You'll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients who need them.
Our Liquid Chromatography/Mass Spectrometry (LC/MS) team are seeking a Scientist with a knack for method development, validation (GxP), and targeted and untargeted analysis using chromatography and mass spectrometric platforms to join their team.
At our organization, we're dedicated to pushing the boundaries of analytical science. Our LC/MS team leverages the synergy between liquid chromatography (LC) and mass spectrometry (MS) to revolutionize how we understand and quantify compounds in complex samples. With a steadfast commitment to excellence and innovation, we tackle challenges across the spectrum of drug discovery to clinical diagnostics, driving advancements that shape the future of healthcare.
Essential Responsibilities:
- Lead the assay development, validation, and sample analysis of biologics, proteins, peptides, ADCs, and/or biomarkers, using various techniques including chromatographic and mass spectrometric assays (LC/MS) for support of preclinical, clinical and product release studies. Experience in mass spectrometry for bioanalysis is required.
- Plan and direct experimental design for junior staff
- Drive bioanalytical projects to align with client timelines
- Frequent communication with clients to discuss technical details and provide project updates.
- Author documents (methods, SOPs, reports)
- Statistical analysis of bioanalytical data
- Review of documentation
- Other duties, as assigned
Additional Responsibilities:
Minimum Preferred Qualifications - Education/Experience (Scientist I):
- Bachelor's degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than six (6) years' experience in a scientific laboratory environment; or
- Master's degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than four (4) years' experience in a scientific laboratory environment; or
- PhD in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than 2 years' experience in a scientific laboratory environment
- Knowledge of regulatory guidance and industry best practices for LC/MS, and other large molecule assays
- Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
- Advanced capabilities in data analysis, data visualization statistical analysis
- Microsoft Word, Excel, Sciex OS/Analyst, MassLynx, XCalibur, Chromeleon, Watson LIMS, JMP, Graphpad Prism
- GDP, GLP, GCLP, GCP
Minimum Preferred Qualifications - Education/Experience (Scientist II):
- Bachelor's degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than eight (8) years' experience in a scientific laboratory environment; or
- Master's degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than six (6) years' experience in a scientific laboratory environment; or
- PhD in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than four (4) years' experience in a scientific laboratory environment
- Knowledge of regulatory guidance and industry best practices for LC/MS, and other large molecule assays
- Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
- Advanced capabilities in data analysis, data visualization statistical analysis
- Microsoft Word, Excel, Sciex OS/Analyst, MassLynx, XCalibur, Chromeleon, Watson LIMS, JMP, Graphpad Prism
- GDP, GLP, GCLP, GCP
Minimum Preferred Qualifications - Education/Experience (Scientist III):
- Bachelor's degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than 12 years' experience in a scientific laboratory environment; or
- Master's degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than ten (10) years' experience in a scientific laboratory environment; or
- PhD in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than eight (8) years' experience in a scientific laboratory environment
- Knowledge of regulatory guidance and industry best practices for LC/MS, and other large molecule assays
- Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
- Advanced capabilities in data analysis, data visualization statistical analysis
- Microsoft Word, Excel, Sciex OS/Analyst, MassLynx, XCalibur, Chromeleon, Watson LIMS, JMP, Graphpad Prism
- GDP, GLP, GCLP, GCP
Minimum Preferred Qualifications - Skills:
- Experience with development, validation and execution of chromatographic and mass spectrometric assays (LC/MS), and/or ability to perform most tasks associated with custom research planning and bench work
- A knack for designing efficient and impactful experiments
- Experience working in a regulated environment, with a thorough understating of GDP, GLP, GCLP, GCP
- Independence, enthusiasm, openness, and adaptability
- Demonstrated effective communication skills
- The ability to inspire others to do their best work and drive results
- Excellent customer service skills (internal and external)
Working Environment:
- Primarily laboratory environment
- Exposure to biological fluids with potential exposure to infectious organisms
- Rare exposure to skin and lung irritants, toxic materials, and hazardous waste
- Personal protective equipment required, such as protective eyewear, garments, and gloves
- Routinely uses standard office equipment such as computers, phones, photocopiers, and filing cabinets
Physical Demands:
- Ability to work in an upright and/or stationary position for up to eight (8) hours per day
- Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment
- Frequent mobility needed
- Frequent crouching, stooping, with frequent bending and twisting of upper body and neck
- Light to moderate lifting and carrying (or otherwise moves) objects including laboratory equipment, laboratory supplies, and laptop computer with a maximum lift of 20 pounds
- Ability to access and use a variety of computer software
- Ability to communicate information and ideas so others will understand, with the ability to listen to and understand information and ideas presented through spoken words and sentences
- Frequently interacts with others to obtain or relate information to diverse groups
- Requires multiple periods of intense concentration
- Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence
- Ability to perform under stress and multi-task
- Regular and consistent attendance
Position Type and Expected Hours of Work:
- This is a full-time position
- Some flexibility in hours is allowed, but the employee must be available during the "core" work hours as published in the BioAgilytix Employee Handbook
- Occasional weekend, holiday, and evening work required
- Occasional travel required
BENEFITS AND OTHER PERKS
Medical Insurance (HDHP with HSA; PPO), Dental Insurance, Vision Insurance, Flexible Spending Account (medical; dependent care), Short Term Disability | Long Term Disability Life Insurance, Paid Time Off (4 weeks per year), Parental Leave, Paid Holidays (12 scheduled; 3 floating), 401k with Employer Match, Employee Referral Program
COMMITMENT TO EQUAL OPPORTUNITY
BioAgilytix provides equal employment opportunities to all employees and applicants for employment without regard to race, color, ancestry, national origin, gender, sexual orientation, marital status, religion, age, disability, gender identity, results of genetic testing, service in the military, or any other group protected by federal, state, or local law.
|
