Bench Scientist Job in Massachusetts (MA), Research and Development Career, Jobs in Aequor
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Bench Scientist job in Cambridge

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Aequor jobs
Massachusetts (MA), Cambridge
Job Code:  24-01231
Employer:  Aequor
Category:  Research and Development

Location
Country:  United States
State:  Massachusetts (MA)
City:  Cambridge
04/17/2024

Description

Job Description
:

BioMedicine Design (BMD) is seeking a highly motivated Biochemist/Molecular Biologist to join Biotherapeutic Expression and Purification group (BEP) in Cambridge, MA. Qualified candidate will play an essential role in a high-energy DNA production and protein expression research laboratory. The group supports non-GMP transient protein lead production across the companies diverse biotherapeutic discovery portfolio to enable the research units and their pre-clinical therapeutic in-vitro and in-vivo needs. The BEP DNA production and protein expression group is looking for a laboratory technician to provide DNA production support for the protein expression and purification activities in BEP. The candidate is expected to have a strong background in molecular biology techniques and experience with nucleic acid production and analysis. The successful candidate will grow bacterial cultures and perform large-scale DNA production activities following standardized protocols. The candidate will be a key contributor to the scientific team responsible for protein expression and purification.

Minimum education experience required:
B.Sc in biological/life sciences, College grad acceptable
or
Associates / Certificate in Biotechnology, 1-2 years exp
or
High School diploma with at least 2 years of relevant laboratory research school

Role Responsibilities
  • Production of plasmid DNA to support transient recombinant protein expression.
  • Conducting routine molecular biology techniques including cell transformations, day cultures, bacterial cultures, Gibson assembly, and digestions.
  • Maintaining reagent and DNA inventory.
  • Operate and maintain automated liquid handlers for plasmid purification, as well as downstream QC applications like NGS and DNA normalizations.
  • Conducting routine DNA characterization and quality control testing using techniques such as gel electrophoresis, fragment analysis, nanodrop, endotoxin testing, and preparation of samples for sequencing analysis (Sanger and NGS).
  • Maintaining daily work records in an organized electronic lab notebook. The candidate should also be proficient in using an online database for inventory management.
  • Effectively communicating with team members to meet strict schedules and deadlines

Required Skills:
  • Production of plasmid DNA
  • Conducting routine molecular biology techniques
  • Maintaining reagent and DNA inventory.

Preferred Skills:
  • Handling Automations
  • Familiarity NGS "Nanopore "

Nice to Have
  • Familiarity with Golden Gate or Gibson assembly

Interview Process:
  • Multiple Panel interviews with camera on.

Position Comments visible to Supplier:
  • Previous experience in a CRO role, preferred.
ref: (24-01231)
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