Senior Investigator, BMD Molecular Cellular Sciences job in Cambridge
|Employer:|| Novartis Pharmaceuticals|
|Category:||Research and Development|
|Job Type:||Full Time|
The Biomarker Development (BMD) group works in close partnership with Novartis and external translational biologists, physicians and project teams to develop precision medicines such that the right patients get the right dose of the right medicine at the right time. Through its world class people and high performing culture, BMD delivers fit for purpose integrated biomarker plans leveraging diverse expertise and knowledge in genetics, genomics, imaging, protein and cellular biology, digital devices, human tissue research, and state of the art data sciences. Our innovative spirit enables the development and application of cutting-edge technologies which address key clinical questions across many disease area strategies. Our high quality methods and data are critical in clinical development to define disease stage or progression, predict the safety or efficacy of medication, select a group of patients who would benefit most from a given therapy, and identify additional clinical indications suitable for a drug, across all indications outside of Oncology. BMD comprises a global group of ~110 associates in Basel Switzerland, Cambridge Massachusetts, East Hanover New Jersey and Shanghai, China.|
As part of the Molecular and Cellular Sciences group we are currently looking for a qualified and highly motivated Biomarker Expert that will:
•Partner with disease area, translational medicine and biomarker experts to define and execute robust "fit for purpose" biomarker strategy that address key scientific and clinical questions. Work with project teams in the interpretation of biomarker data in the context of clinical trial results.
•Drive the scientific, technical development and implementation of cellular and soluble biomarker assays by applying innovative, high valued technologies and suitable methods in data analysis.
•Identify cellular and soluble biomarker needs and gaps in early projects and leading the evaluation and implementation of innovative technical solutions.
•As part of a global group lead a cross functional team of scientists
•Partner with outsourcing functions to identify and evaluate new CROs according to project, technical and quality needs, drive transitioning and monitoring of internally developed assays to external vendors
•Contribute to BMD scientific, technical, organizational and people leadership goals
•Ensure quality and timelines of deliverables
•Manage projects according to the appropriate SOPs and guidelines in compliance with Novartis quality expectations.Requirements:
•PhD or MD in Immunology or cell biology or equivalent related experience and 5+ years of industry experience in immunology or related fields
•Extensive understanding, knowledge and experience in flow cytometry, ligand binding assay and/or mass spectrometry technologies and applications
•Extensive experience in the implementation of biomarker analyses in clinical studies according to international guidelines
•Proven ability to work and lead in a global organizational and scientific environment
•Fluent in written and spoken English, excellent communication and presentations skills
•Solid understanding of tools, practices and processes employed in early clinical trial settings and drug development
•Demonstrated leadership experience managing global team of laboratory associates.
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